Current approaches for dose optimization of arc proton therapy (arcPT) plans suffer from optimization times ranging from several minutes to hours. In the context of adaptive proton therapy, we aim to speed up the plan reoptimization process. To achieve this, instead of optimizing a new arcPT plan from scratch for each adaptive fraction, we propose to update the initial spot positions and their corresponding energies to the new anatomy of the day. Following this, we proceed to re-optimize only the most pertinent spot weights, which comprise less than 15% of all the spots. Currently, this approach allows arcPT plans to be adapted in less than 1 hour on a laptop (future evaluations will require more powerful computers).
Project funded by Wallonia region under grand agreement MECATECH / BIOWIN No. 8090 (Proton Arc Therapy)
Responsible(s)
- Benjamin Roberfroid MIRO/IREC/UCLouvain (benjamin.roberfroid@uclouvain.be)
- Ana Barragan MIRO/IREC/UCLouvain (ana.barragan@uclouvain.be)
- John Lee MIRO/IREC/UCLouvain (john.lee@uclouvain.be)
- Edmond Sterpin MIRO/IREC/UCLouvain - PARTICLE/KULeuven (edmond.sterpin@uclouvain.be)
Related publication(s)
- In progress…
